La Jolla Mom
Columbia, where you’ll find most of downtown's tallest buildings and a lot of the waterfront attractions like the USS Midway Museum and the Maritime Museum.
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The Core neighborhood is the heart of San Diego’s government, as well as a commercial center with some great shopping.
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Cortez Hill is quieter and mostly residential, though it’s also the home of the historic (and notably tall) El Cortez hotel.
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The Gaslamp Quarter was the birthplace of downtown and is the epicenter of nightlife in San Diego. Many choose to stay in Gaslamp San Diego hotels for this reason.
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Little Italy was originally home to scores of fishers from Italy but is now one of the city’s go-to areas for the best food and drink.
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